Increased jugular bulb saturation is associated with poor outcome in traumatic brain injury
| Autor: | C S A Macmillan, Peter J. D. Andrews, Valerie Easton |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Male Adolescent Intracranial Pressure Traumatic brain injury Short Report Central nervous system disease Intensive care medicine Humans Cerebral perfusion pressure Aged Monitoring Physiologic Intracranial pressure business.industry Glasgow Outcome Scale Glasgow Coma Scale Middle Aged Prognosis medicine.disease Psychiatry and Mental health Brain Injuries Cerebrovascular Circulation Anesthesia Injury Severity Score Female Surgery Neurology (clinical) Jugular Veins business |
| Zdroj: | Journal of Neurology, Neurosurgery & Psychiatry. 70:101-104 |
| ISSN: | 0022-3050 |
| DOI: | 10.1136/jnnp.70.1.101 |
| Popis: | The objective was to compare secondary insults, particularly decreases in jugular bulb oxyhaemoglobin saturation (SjO2), during intensive care in patients with "poor" and "good" outcomes 12months after traumatic brain injury. A prospective observational study of patients' physiological data collected each minute from multimodality monitoring was carried out. Patients had duration of physiological insults quantified as a percentage of their validated monitoring time (once invalid data due to technical reasons were removed). Treatment protocols were designed to minimise secondary insults by maintaining intracranial pressure (ICP) less than 20 mm Hg, and cerebral perfusion pressure (CPP) greater than 70 mm Hg, with prompt correction of hypoxia and pyrexia. Twelve months after injury patients' neurological function was assessed using the Glasgow outcome scale (GOS). A poor outcome was defined as GOS 1 to 3 (group 1) and a good outcome as GOS 4 and 5 (group 2). Seventy five patients (64 male), median age of 34 years (range 15 to 70), were studied. At 12 months 33 patients had a poor outcome (group 1), and 42 a good outcome (group 2). Group 1 spent proportionately more time with SjO2 greater than 75% compared with group 2 (p |
| Databáze: | OpenAIRE |
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