Potential benefits of pentoxifylline on wound healing
| Autor: | Hossein Khalili, Motahareh Ahmadi |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Vasodilator Agents Skin flap Recurrent aphthous stomatitis Surgical Flaps Pentoxifylline 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine Animals Humans Pharmacology (medical) General Pharmacology Toxicology and Pharmaceutics Burn scar Pressure Ulcer Wound Healing integumentary system business.industry General Medicine Colorectal anastomosis Mucocutaneous leishmaniasis medicine.disease Surgery 030220 oncology & carcinogenesis Soft tissue injury business Wound healing Burns medicine.drug |
| Zdroj: | Expert review of clinical pharmacology. 9(1) |
| ISSN: | 1751-2441 |
| Popis: | In this review, potential benefits of pentoxifylline (PTX) on wound healing have been evaluated. All available experimental and clinical studies examined effects of PTX on wound healing have been included. No time limitation was considered and all studies up to writing the manuscript were included. Administration of oral or parenteral PTX showed beneficial effects on the healing of colorectal anastomosis, post burn scar, radiation-induced skin/soft tissue injury, venous ulcers, recurrent aphthous stomatitis and cutaneous/mucocutaneous leishmaniasis. Data regarding effect of PTX on skin flap survival are conflicting. Only few evidences support promising effects of PTX in pressure ulcer, skin developing injury and burn. |
| Databáze: | OpenAIRE |
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