Assessment of circulating biochemical markers and antioxidative status in acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) patients
| Autor: | Mahmood Rasool, Suleman Sani, Mahmood Husain Qazi, Mohammad Amjad Kamal, Muhammad Asif, Abdul Manan, Shahzad Farooq, Zafar Iqbal, Arif Malik, Aysha Shaukat, Abrar Hussain |
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| Jazyk: | angličtina |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment MDA medicine.disease_cause Antioxidants Superoxide dismutase chemistry.chemical_compound Electrolytes AML Internal medicine medicine chemistry.chemical_classification Leukemia Agricultural and Biological Sciences(all) biology business.industry Glutathione peroxidase Vitamin E Myeloid leukemia Glutathione medicine.disease Malondialdehyde Endocrinology chemistry Oxidative stress Immunology biology.protein Original Article General Agricultural and Biological Sciences business ALL |
| Zdroj: | Saudi Journal of Biological Sciences. (1):106-111 |
| ISSN: | 1319-562X |
| DOI: | 10.1016/j.sjbs.2014.09.002 |
| Popis: | Various circulating biochemical markers are indicators of pathological state in leukemia and its subtypes. Increased oxidative stress and decreased antioxidant factors portray clear image associated with malignancies during subtypes of leukemia. In this research work we investigated the inter-relationship among the subtypes of leukemia with circulating biochemical markers and oxidative stress in the Pakistani population. This research work was conducted on a total number of 70 subjects in which 20 were control participants and 50 were suffering from leukemia and divided into two subtypes (ALL and AML). Various circulating biomarkers were investigated including hematological, hepatic and renal profiles as well as oxidative stress markers, electrolytes and vitamins C and E. Results show that vitamin E was found to be decreased in diseased sub-types (P |
| Databáze: | OpenAIRE |
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