Occupational Argyria of the Nasal Mucosa
| Autor: | Alessandra Filosa, Maria Paola Mariani, Luigi Fasanella, Gerardo Ferrara |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Nasal cavity
Adult Male medicine.medical_specialty Pathology Silver Mucous membrane of nose Stain Argyria Pathology and Forensic Medicine 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Occupational Exposure Biopsy Medicine Humans Sine qua non Clinicopathologic Correlation medicine.diagnostic_test business.industry medicine.disease Dermatology Melanosis Precancerous condition Nasal Mucosa medicine.anatomical_structure Oncology Otorhinolaryngology 030220 oncology & carcinogenesis Histopathology sense organs business |
| Zdroj: | Head and neck pathology. 12(2) |
| ISSN: | 1936-0568 |
| Popis: | A biopsy specimen from the nasal mucosa of a 37-year-old man disclosed a subepithelial accumulation of black granules mainly running parallel to the surface in the absence of any inflammatory infiltrate. Since the mucosal pigment was negative with Perls’ stain and resisted to melanin bleach, an exogenous pigmentation was suspected. The biopsy specimen had been taken because of a diffuse steel-blue pigmentation of the nasal mucosa, incidentally discovered during routine clinical examination. A diagnosis of occupational argyria of the nasal mucosa was finally made since the patient was a silver cleaner. Argyria is a rare cause of nasopharyngeal mucosal pigmentation; it is not a precancerous condition, but it can be mistaken for a melanosis or a melanocytic tumor both clinically and histopathologically. Clinicopathological correlation is mandatory, since the final diagnosis is based on a history of chronic silver exposure. |
| Databáze: | OpenAIRE |
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