The association between overall and abdominal adiposity and depressive mood: A cross-sectional analysis in 6459 participants
| Autor: | Tahani Alshehri, Frits R. Rosendaal, Yuri Milaneschi, Saskia le Cessie, Dennis O. Mook-Kanamori, Brenda W.J.H. Penninx, Sebastiaan C. Boone, Renée de Mutsert |
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| Přispěvatelé: | Psychiatry, APH - Mental Health, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, APH - Digital Health |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Waist Cross-sectional study Endocrinology Diabetes and Metabolism Population Body fat distribution 03 medical and health sciences 0302 clinical medicine Endocrinology Risk Factors Internal medicine Medicine Humans Obesity education Biological Psychiatry Body mass index Adiposity Aged Netherlands education.field_of_study Endocrine and Autonomic Systems business.industry Depression Depressive disorder Confounding Abdominal fat Odds ratio Middle Aged medicine.disease Confidence interval 030227 psychiatry Psychiatry and Mental health Affect Cross-Sectional Studies Obesity Abdominal Female business 030217 neurology & neurosurgery |
| Zdroj: | Psychoneuroendocrinology, 110 Alshehri, T, Boone, S, de Mutsert, R, Penninx, B, Rosendaal, F, le Cessie, S, Milaneschi, Y & Mook-Kanamori, D 2019, ' The association between overall and abdominal adiposity and depressive mood : A cross-sectional analysis in 6459 participants ', Psychoneuroendocrinology, vol. 110, 104429 . https://doi.org/10.1016/j.psyneuen.2019.104429 Psychoneuroendocrinology, 110:104429. Elsevier Limited |
| ISSN: | 0306-4530 |
| DOI: | 10.1016/j.psyneuen.2019.104429 |
| Popis: | Objective We aimed to evaluate the association between measures of adiposity with depressive mood and specific depressive symptoms. Methods This study was performed in the Netherlands Epidemiology of Obesity (NEO) study, a population-based study that consists of 6671 middle-aged individuals. We examined the association between measures of overall adiposity (BMI and total body fat), and abdominal adiposity (waist circumference and visceral adipose tissue), with depressive mood severity subgroups and 30 depressive symptoms. Multinomial logistic regression was performed adjusting for potential confounding. Results Measures of adiposity were associated with depressive mood in a graded fashion. Total body fat showed the strongest association with mild (Odds Ratio (OR): 1.59 per standard deviation, 95% Confidence Interval (95% CI): 1.41–1.80) and moderate to very severe (OR: 1.97, 95% CI: 1.59–2.44) depressive mood. Regarding individual symptoms of depressive mood, total body fat was associated with most depressive symptoms (strongest associations for hyperphagia and fatigability). Conclusions In the general population, overall and abdominal adiposity measures were associated with depressive mood. This association encompasses most of the depressive symptoms and appeared to be the strongest with specific ‘’atypical’’ neurovegetative symptoms, which may be an indication of an alteration in the energy homeostasis. |
| Databáze: | OpenAIRE |
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