HLA-A, -B, -C, -DRB1 and -DQB1 allele and haplotype frequencies of 1463 umbilical cord blood units typed in high resolution from Bogotá, Colombia

Autor:	Ana-María Perdomo-Arciniegas, Bernardo Camacho-Rodríguez, Iván Aurelio Páez-Gutiérrez, David Guillermo Hernández-Mejía, Diana Vanegas
Rok vydání:	2019
Předmět:	musculoskeletal diseases 0301 basic medicine medicine.medical_treatment Immunology Population HLA-C Antigens Human leukocyte antigen Hematopoietic stem cell transplantation Colombia Biology Umbilical cord 03 medical and health sciences 0302 clinical medicine Gene Frequency medicine HLA-DQ beta-Chains Humans Immunology and Allergy Allele education Allele frequency education.field_of_study HLA-A Antigens Histocompatibility Testing Haplotype Hematopoietic Stem Cell Transplantation Exons General Medicine Fetal Blood Molecular biology Tissue Donors HLA-A Genetics Population 030104 developmental biology medicine.anatomical_structure Haplotypes Genetic Loci HLA-B Antigens HLA-DRB1 Chains 030215 immunology
Zdroj:	Human Immunology. 80:425-426
ISSN:	0198-8859
DOI:	10.1016/j.humimm.2019.03.006
Popis:	Allele and haplotype frequencies were calculated from 1463 umbilical cord blood (UCB) units, from Bogota (Colombia) donors, HLA-typed in high resolution. This is the first report using allele-level typed colombian samples of five HLA loci related to hematopoietic stem cell transplantation (HLA-A, -B, -C, -DRB1 and -DQB1). The most frequent haplotype found in our sample was A*24:02g ∼ B*35:43g ∼ C*01:02g ∼ DRB1*04:07g ∼ DQB1*03:02g (4.14%). Our data are available at the Allele Frequencies Net Database under the code AFND3604.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059fe4122727e50305533e135f4d4a53 https://doi.org/10.1016/j.humimm.2019.03.006 Zobrazit plný text záznamu Full Text from ScienceDirect