Neonatal lupus presenting as a non-specific rash in primary care
| Autor: | Corinna J. Rea, Heather Bernard |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Anti-nuclear antibody Case Report Administration Cutaneous Asymptomatic Infant Newborn Diseases Autoimmune Diseases 03 medical and health sciences 0302 clinical medicine Lupus Erythematosus Cutaneous medicine Humans Neonatal lupus erythematosus skin and connective tissue diseases 030203 arthritis & rheumatology Autoimmune disease Leukopenia Primary Health Care business.industry Infant Newborn Erythematous papule General Medicine Exanthema medicine.disease Rash Dermatology medicine.anatomical_structure Scalp Female Steroids medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | BMJ Case Rep |
| ISSN: | 1757-790X |
| DOI: | 10.1136/bcr-2020-237463 |
| Popis: | Neonatal lupus erythematosus is a rare autoimmune disease caused by passive transplacental acquisition of maternal autoantibodies manifesting in cutaneous, cardiac, haematological and hepatobiliary abnormalities. The hallmark dermatological finding is erythematous annular lesions with a predilection for photo-exposed areas of the skin. We present a case of a female infant born to a mother with Sjogren’s syndrome, who initially presented to an ambulatory care setting with non-specific erythematous papules involving the face and scalp. Within 6 days the rash changed in appearance, consisting of widespread erythematous annular and polycyclic lesions with central violaceous clearing and atrophy. Serological tests revealed asymptomatic anemia and leukopenia, elevated liver enzymes, and positive antinuclear antibodies (ANA) and anti-SSb/La antibodies. Further cardiac evaluation was normal. She was managed conservatively in the outpatient setting with topical steroids, avoidance of sunlight and fluorescent light exposure, and primary care, rheumatological and dermatological follow-up. |
| Databáze: | OpenAIRE |
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