PSIII-11 The effect of GALR2 genotype and differing implant strategies on blood metabolite concentrations in finishing steers
Autor: | Mara Hirchert, Kasey R Maddock Carlin, Ellie S Anderson, Jerica R Hall, Carl R Dahlen, Alison K Ward, Kendall C Swanson |
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Rok vydání: | 2020 |
Předmět: | |
Zdroj: | J Anim Sci |
ISSN: | 1525-3163 0021-8812 |
DOI: | 10.1093/jas/skaa054.419 |
Popis: | The neuropeptide receptor galanin receptor 2 (GALR2) is involved in appetite regulation and is therefore a potential target for marker-assisted management of finishing cattle. The objective of this study was to determine the interaction between implant strategy and GALR2 genotype on the metabolic status of feedlot steers. Angus crossbred steers (n = 93) were selected for the study based on GALR2 c.-199G >T genotype (n = 19 GG, 36 TT and 38 TG steers). Steers were blocked by initial body weight into two groups (248 ± 50 and 293± 43 kg) and finished for 166 or 202 days. Steers were assigned one of two implant strategies in a 2 (implant) × 3 (genotype) factorial design. The implant strategies were: one implant of Revalor-S (Merk, New Jersey) on day 77 of finishing (1X) or two implants with the first on day 0 and the second on day 77 (2X). All steers were fed a standard feedlot ration throughout the study. Blood samples were collected every 28 days. Serum samples were analyzed for blood urea nitrogen (BUN) and glucose concentration. Data were analyzed using the mixed procedure of SAS with repeated measures and significance was set at P < 0.05. Day × Implant interaction had a significant effect on BUN (P = 0.0035), and day × genotype had a significant effect on serum glucose concentration (P = 0.0049). There was no effect of implant × genotype interaction for BUN or glucose (P > 0.05). On days 84 and 140 glucose concentration was greater in GG steers than GT steers (P < 0.05) and tended to be greater than TT steers (P ≤ 0.0667). We conclude that there is no interaction between implant strategy and GALR2 genotype on metabolism in finishing steers. |
Databáze: | OpenAIRE |
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