RESPONSES OF MOLECULAR INDICATORS OF EXPOSURE IN MESOCOSMS: COMMON CARP (CYPRINUS CARPIO) EXPOSED TO THE HERBICIDES ALACHLOR AND ATRAZINE
| Autor: | Lina W. Chang, F. Jerry deNoyelles, Scott W. Campbell, John R. Meier, Denise A. Gordon, David L. Lattier, David W. Graham, Charles W. Knapp, Gregory P. Toth |
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| Rok vydání: | 2005 |
| Předmět: |
Male
Carps Time Factors Health Toxicology and Mutagenesis Biological Availability Gene Expression Cyprinus Vitellogenins Common carp chemistry.chemical_compound Vitellogenin Acetamides Cytochrome P-450 CYP1A1 Animals Environmental Chemistry Ecotoxicology Atrazine Carp Ecosystem biology Herbicides Alachlor Pesticide biology.organism_classification Liver chemistry Environmental chemistry biology.protein Female Water Pollutants Chemical DNA Damage |
| Zdroj: | Environmental Toxicology and Chemistry. 24:190 |
| ISSN: | 1552-8618 0730-7268 |
| DOI: | 10.1897/03-509.1 |
| Popis: | Common carp (Cyprinus carpio) were treated in aquatic mesocosms with a single pulse of the herbicides atrazine or alachlor to study the bioavailability and biological activity of these herbicides using molecular indicators: Liver vitellogenin gene expression in male fish for estrogenic activity, liver cytochrome P4501A1 gene expression, and DNA damage in blood cells using the single-cell gel electrophoresis method. Both alachlor and atrazine showed dose-related increases in DNA strand breaks at environmentally relevant concentrations ( |
| Databáze: | OpenAIRE |
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