Surgical site infection in elective colonic and rectal resections: effect of oral antibiotics and mechanical bowel preparation compared with mechanical bowel preparation only
| Autor: | Manoj J. Raval, Naomi Kasteel, Paul Terry Phang, S. D. Wexner, Amandeep Ghuman, Ahmer A. Karimuddin, Carl J. Brown |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class Antibiotics Administration Oral Subgroup analysis 030230 surgery Preoperative care 03 medical and health sciences 0302 clinical medicine Preoperative Care medicine Humans Surgical Wound Infection Antibiotic prophylaxis Retrospective Studies business.industry Cathartics Gastroenterology Retrospective cohort study Antibiotic Prophylaxis Colorectal surgery Surgery Anti-Bacterial Agents Metronidazole Elective Surgical Procedures 030211 gastroenterology & hepatology business Elective Surgical Procedure medicine.drug |
| Zdroj: | Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and IrelandReferences. 22(11) |
| ISSN: | 1463-1318 |
| Popis: | AIM Surgical site infections are disproportionately common after colorectal surgery and may be largely preventable. The objective of this retrospective cohort study was to determine the effect of oral antibiotics and mechanical bowel preparation on surgical site infections. METHOD A retrospective study of a consecutive series of elective colonic and rectal resections following an Enhanced Recovery After Surgery pathway, which also included mechanical bowel preparation, from 1 September 2014 to 30 September 2017. The addition of oral antibiotics (neomycin and metronidazole) to the mechanical bowel preparation procedure was assessed. Development of surgical site infections within 30 days was the main outcome measured. The secondary outcome was assessment of possible surgical site infection predictors. RESULTS Seven-hundred thirty-two patients were included: 313 (43%) preintervention (mechanical bowel preparation only); and 419 (57%) postintervention (mechanical bowel preparation plus oral antibiotics). Surgical site infection rates preintervention and. postintervention were: overall, 20.8% vs 10.5%, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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