Overview on immobilization of enzymes on synthetic polymeric nanofibers fabricated by electrospinning
| Autor: | Anjum Hamid Rather, Faheem A. Sheikh, Rumysa Saleem Khan, Mushtaq A. Beigh, Taha Umair Wani |
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| Rok vydání: | 2021 |
| Předmět: |
chemistry.chemical_classification
Materials science Immobilized enzyme Polymers Composite number Nanofibers Bioengineering Nanotechnology Polymer Electrochemical Techniques Enzymes Immobilized Applied Microbiology and Biotechnology Electrospinning chemistry Surface-area-to-volume ratio Biocatalysis Nanofiber Porosity Biotechnology |
| Zdroj: | Biotechnology and bioengineeringREFERENCES. 119(1) |
| ISSN: | 1097-0290 |
| Popis: | The arrangement of supports has a significant impact on the efficiency of immobilized enzymes. Fibrous materials can be one of the most desirable supports for enzyme immobilization. This is due to their high surface area to volume ratio, internal porosity, ease of handling, and high mechanical stability, all of which allow a higher enzyme loading, release and finally leads to better catalytic efficiency. Fortunately, the enzymes can reside deep inside individual nanofibers to remain encapsulated and retain their three-dimensional structure. These properties can protect the enzyme's tolerance against harsh conditions such as pH variations and high temperature, probably enhancing the enzyme's stability. This review article will discuss the immobilization of enzymes on synthetic polymers, which are fabricated into nanofibers by electrospinning. Electrospinning is rapidly gaining popularity as one of the most practical ways to make polymer, metal oxide, and composite fibers. As a result, there is interest in using electrospun nanofibers to immobilize enzymes. However, only a few methods can be used to examine the impact of nanofiber surfaces on the immobilized enzymes' behaviors. Furthermore, present research on electrospun nanofibers for enzyme immobilization is primarily limited to the lab scale and is still pending. The primary future research objectives in electrospun nanofibers for enzyme immobilization include increasing yield to transfer biological products into commercial applications. This article is protected by copyright. All rights reserved. |
| Databáze: | OpenAIRE |
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