Female infertility, infertility-associated diagnoses, and comorbidities: a review
Autor: | Jessie Dorais, Erica Johnstone, James M. Hotaling, Bob Silver, C. Matthew Peterson, Brent M. Hanson |
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Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: |
Infertility
Adult medicine.medical_specialty medicine.drug_class Genital Neoplasms Female Reproductive medicine Disease Comorbidity Fertilization in Vitro 03 medical and health sciences 0302 clinical medicine Breast cancer Internal medicine Genetics medicine Humans Assisted Reproduction Technologies Genetics (clinical) Fertility drugs Gynecology 030219 obstetrics & reproductive medicine business.industry Endometrial cancer Mental Disorders Reproduction Female infertility Obstetrics and Gynecology General Medicine medicine.disease Reproductive Medicine 030220 oncology & carcinogenesis Female business Ovarian cancer Infertility Female Developmental Biology Polycystic Ovary Syndrome |
Popis: | The purpose of the study is to evaluate existing literature for possible associations between female infertility, infertility-associated diagnoses, and the following areas of disease: psychiatric disorders, breast cancer, ovarian cancer, endometrial cancer, cardiovascular disease, and metabolic dysfunction.The design of the study is a literature review. The patients were women included in 26 selected studies due to a diagnosis of infertility or a reproductive disorder associated with infertility. This study has no interventions, and the main outcome measure is the association between female infertility or a related diagnosis and psychiatric disorders, breast cancer, ovarian cancer, endometrial cancer, cardiovascular disease, and metabolic dysfunction.Female infertility and related reproductive disorders may have ramifications for women beyond reproductive health. An analysis of publications shows that women with infertility had higher rates of psychiatric disorders and endometrial cancer than the general population [1-10]. Data is conflicting about whether infertile women are at increased risk for breast cancer and ovarian cancer [7, 8, 10-20]. A generalized diagnosis of infertility was not clearly associated with an increased risk of cardiovascular disease or metabolic dysfunction, but women with infertility related to polycystic ovarian syndrome (PCOS) do appear more likely to develop cardiovascular disease and metabolic disorders such as diabetes than the general population [16, 21-26].Female infertility and associated diagnoses have overall health implications. Beyond treatment of patients' immediate reproductive needs, healthcare professionals must be aware of the broader health impact of specific causes of infertility in order to provide accurate counseling regarding long-term risk. |
Databáze: | OpenAIRE |
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