Primary Bone Lymphoma: A Case Series and Review of Literature

Autor: Sudhanshu Mulay, Lukas Delasos, James J. Vredenburgh, Poorva Bindal, Aakash Desai
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Case Reports in Hematology
Case Reports in Hematology, Vol 2020 (2020)
ISSN: 2090-6579
2090-6560
Popis: Primary bone lymphoma (PBL) is a subtype of lymphoma that exclusively affects skeletal tissue. Despite the relatively common involvement of skeletal structures as a manifestation of non-Hodgkin’s lymphoma (NHL), primary and exclusive involvement of the skeletal system is rare. The prevalence of PBL is estimated to be 3–7% amongst primary bone tumors and less than 2% amongst all lymphomas in adults. However, the definition of primary bone lymphoma has been inconsistent over time. Within our institution, we identified four cases of primary bone lymphoma based on diagnostic criteria formed from the general consensus of multiple organizations, including the World Health Organization (WHO) and International Extranodal Lymphoma Study Group (IELSG). Here, we discuss the distinct characteristics amongst these cases in addition to performing a systematic review of current literature regarding this lymphoproliferative entity.
Databáze: OpenAIRE