The effect of egg and its derivatives on vascular function: A systematic review of interventional studies
| Autor: | Ali Saneei Totmaj, Hadi Emamat, Azita Hekmatdoost, Hadith Tangestani |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
food.ingredient Eggs Endocrinology Diabetes and Metabolism Physiology 030209 endocrinology & metabolism Pulse Wave Analysis 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine food Yolk Humans Medicine Adverse effect Pulse wave velocity Clinical Trials as Topic 030109 nutrition & dietetics Nutrition and Dietetics business.industry Cholesterol Lutein Egg intake Whole egg chemistry Cardiovascular Diseases embryonic structures business Vascular function |
| Zdroj: | Clinical Nutrition ESPEN. 39:15-21 |
| ISSN: | 2405-4577 |
| DOI: | 10.1016/j.clnesp.2020.06.016 |
| Popis: | Cardiovascular diseases (CVDs) are considered as a major cause of health loss for all regions of the world. Atherosclerosis is one of the most important underlying causes of CVDs. Vascular dysfunction is the primary marker of atherosclerosis. Various studies have investigated the effect of egg intake on CVDs. This study aimed to determine the effect of egg and its derivatives consumption on vascular function.Using a comprehensive search strategy, the searching was conducted on PubMed, Scopus and Google Scholar search engines resources (from inception up to Feb 2020). Intended exposure and outcome were egg or its derivatives intake, and vascular function measuring methods, respectively.A total of 35 papers were found through search databases. Finally, seven trials were included, which were published between 2005 and 2018. Results showed that acute and chronic consumption of whole eggs did not have a significant adverse effect on flow-mediated dilatation (FMD). Also, lutein-enriched egg yolk and egg ovalbumin-derived protein hydrolysate did not have significant positive effects on FMD and pulse wave velocity (PWV), respectively. However, one month egg-yolk-derived phospholipid (PL) preparation intervention increased FMD by 3.4% (p 0.05), and replacing a portion of a glucose challenge with whole eggs or egg whites improved postprandial FMD (p 0.05).We concluded that consumption of whole egg, despite being rich in cholesterol, has no adverse effect on vascular function, and even some of egg derivatives may improve vascular function. Further research is needed to justify the potential effects of egg or its derivatives on vascular function. |
| Databáze: | OpenAIRE |
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