Meningeal and Visual Pathway Magnetic Resonance Imaging Analysis after Single and Repetitive Closed-Head Impact Model of Engineered Rotational Acceleration (CHIMERA)-Induced Disruption in Male and Female Mice

Autor: Eileen H. McNamara, Andrew Knutsen, Alexandru Korotcov, Asamoah Bosomtwi, Jiong Liu, Amanda H. Fu, Claire Kostelnik, Antigone A. Grillakis, Haley Spencer, Bernard Dardzinski, Joseph T. McCabe
Rok vydání: 2022
Předmět:
Zdroj: Journal of neurotrauma. 39(11-12)
ISSN: 1557-9042
Popis: The consequences of forceful rotational acceleration on the central nervous system are not fully understood. While traumatic brain injury (TBI) research primarily has focused on effects related to the brain parenchyma, reports of traumatic meningeal enhancement in TBI patients may possess clinical significance. The objective of this study was to evaluate the meninges and brain for changes in dynamic contrast enhancement (DCE) magnetic resonance imaging (MRI) following closed-head impact model of engineered rotational acceleration (CHIMERA)-induced cerebral insult. Adult male and female mice received one (1 ×
Databáze: OpenAIRE