Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report
| Autor: | Svetomir N. Markovic, Nazanin Yeganeh Kazemi, Melanie C. Bois, Atta Behfar, Christopher Charles Jain, Kenneth R. Olivier |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Pathology
medicine.medical_specialty MCPyV Merkel cell polyomavirus Heart block medicine.medical_treatment PD-L1 programmed cell death ligand 1 MCC Merkel cell carcinoma Merkel cell polyomavirus Case Report 030204 cardiovascular system & hematology PET positron emission tomography 03 medical and health sciences 0302 clinical medicine PD-L1 FDG [18F]-fluorodeoxyglucose Biopsy CM cardiac metastases Medicine 030212 general & internal medicine lcsh:R5-920 biology medicine.diagnostic_test business.industry Merkel cell carcinoma food and beverages Immunotherapy medicine.disease biology.organism_classification Lymphoma CT computed tomography biology.protein Skin cancer business lcsh:Medicine (General) MRI magnetic resonance imaging |
| Zdroj: | Mayo Clinic Proceedings: Innovations, Quality & Outcomes Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 3, Iss 4, Pp 510-516 (2019) |
| ISSN: | 2542-4548 |
| Popis: | Merkel cell carcinoma (MCC) is a rare, rapidly proliferating skin cancer that commonly metastasizes to regional lymph nodes. We present the case of a 73-year-old woman with a history of MCC and non-Hodgkin B-cell lymphoma who presented with second-degree heart block (Mobitz type II) caused by an interatrial mass. Temporary pacing was required before biopsy, which revealed metastatic MCC. Treatment included permanent pacing, anti-programmed cell death ligand 1 immunotherapy, and radiation to the heart resulting in notable decrease in tumor size and normalized cardiac rhythm. |
| Databáze: | OpenAIRE |
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