Cancer drugs inhibit morphogenesis in the human fungal pathogen, Candida albicans
| Autor: | Nitin M. Chauhan, Madhushree M. Routh, S. Mohan Karuppayil |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Pathology
medicine.medical_specialty Antifungal Agents Hypha Short Communication Cancer drugs Morphogenesis lcsh:QR1-502 Hyphae Antineoplastic Agents Microbial Sensitivity Tests Microbiology lcsh:Microbiology Candida albicans Medicine Humans cancer drugs Microscopy biology Antifungal antibiotic business.industry Drug Repositioning Cancer Fungal pathogen medicine.disease biology.organism_classification antifungal antibiotics Yeast morphogenetic switching business |
| Zdroj: | Brazilian Journal of Microbiology Brazilian Journal of Microbiology v.44 n.3 2013 Sociedade Brasileira de Microbiologia (SBM) instacron:SBM Brazilian Journal of Microbiology, Vol 44, Iss 3, Pp 855-859 (2013) Brazilian Journal of Microbiology, Volume: 44, Issue: 3, Pages: 855-859, Published: SEP 2013 |
| ISSN: | 1678-4405 |
| Popis: | Candida infections are very common in cancer patients and it is a common practice to prescribe antifungal antibiotics along with anticancer drugs. Yeast to hyphal form switching is considered to be important in invasive candidiasis. Targeting morphogenetic switching may be useful against invasive candidiasis. In this study, we report the antimorphogenetic properties of thirty cancer drugs. |
| Databáze: | OpenAIRE |
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