Influence of housing conditions on pregnancy outcome in cynomolgus monkeys (Macaca fascicularis)

Autor: R. Boot, A. B. Leussink, R. F. Vlug
Rok vydání: 1985
Předmět:
Zdroj: Laboratory animals. 19(1)
ISSN: 0023-6772
Popis: Female cynomolgus monkeys ( Macaca fascicularis) were kept under 3 different housing conditions: individually in type A cages (45 × 45 × 60 cm), individually in type B cages (70 × 70 × 100 cm) and as couples in type B cages. Primigravida did not show early embryonic mortality, differing significantly from 11·5% early losses in multigravida. Early embryonic mortality was not affected by housing condition. Further reproductive failure rates did not differ significantly for primigravid (18·5%) and multigravid females (24·0%), though abortion tended to occur more frequently in primigravida. Perinatal mortality (16·1%) accounted for most of the losses under each housing condition. More successful pregnancies (90%) were recorded for females housed individually in type B cages than for females housed in type A cages (68%). About 50% of the couples originally established remained until weaning of their infants, yielding 77% viable offspring. For multigravid females statistical evaluation showed a significant effect of housing conditions on reproductive outcome ( x2-test 0·01 < P < 0·05) that could be entirely attributed to low losses in females housed individually in type B cages. It is concluded that housing conditions can have a profound influence on reproductive success in cynomolgus monkeys.
Databáze: OpenAIRE