Peptide-mediated regulation of the allergic immune response
| Autor: | Gerard F. Hoyne, J. R. Lamb |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
0301 basic medicine
Th2 response animal diseases medicine.medical_treatment Immunology chemical and pharmacologic phenomena Peptide Allergic sensitization 03 medical and health sciences 0302 clinical medicine Immune system Hypersensitivity Animals Humans Immunology and Allergy Medicine chemistry.chemical_classification business.industry Cell Biology Immunotherapy biochemical phenomena metabolism and nutrition 030104 developmental biology chemistry Desensitization Immunologic bacteria Th1 response Peptides business Reprogramming Forecasting 030215 immunology |
| Zdroj: | Immunology and Cell Biology. 74:180-186 |
| ISSN: | 0818-9641 |
| DOI: | 10.1038/icb.1996.25 |
| Popis: | A major key to successful immunotherapy may depend on altering the qualitative nature of the immune response in allergic patients. In this review we examine how immune responses to environmental allergens are regulated, and the mechanisms used by the immune system to prevent allergic sensitization. We also discuss future prospects of using allergen-derived peptides in immunotherapy and the possibility of 'reprogramming' the immune responses by immunizing under conditions that promote Th1 responses instead of Th2 responses. |
| Databáze: | OpenAIRE |
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