Stress and survival after cancer: a prospective study of a Finnish population-based cohort
| Autor: | Christoffer Johansen, Pernille Envold Bidstrup, P K Verkasalo, Kirsten Frederiksen, Kumi Saito-Nakaya, Naoki Nakaya, Eero Pukkala, Jaakko Kaprio, Markku Koskenvuo, Yosuke Uchitomi, Susanne Oksbjerg Dalton |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Cancer Research Epidemiology Cohort Studies Life Change Events 03 medical and health sciences 0302 clinical medicine Breast cancer Neoplasms Surveys and Questionnaires Medicine Humans 030212 general & internal medicine Prospective cohort study Finland Proportional Hazards Models business.industry Proportional hazards model Hazard ratio Cancer Middle Aged medicine.disease Confidence interval Oncology 030220 oncology & carcinogenesis Cohort Female business Stress Psychological Cohort study Demography |
| Zdroj: | Saito-Nakaya, K, Bidstrup, P E, Nakaya, N, Frederiksen, K, Dalton, S O, Uchitomi, Y, Verkasalo, P, Koskenvuo, M, Pukkala, E, Kaprio, J & Johansen, C 2012, ' Stress and survival after cancer: A prospective study of a Finnish population-based cohort ', Cancer Epidemiology, vol. 36, no. 2, pp. 230-235 . https://doi.org/10.1016/j.canep.2011.04.008 |
| ISSN: | 1877-783X |
| Popis: | Stress has been suggested to reduce survival after cancer, but the results of previous studies have been contradictory. We investigated the hypothesis in a national cohort of adults in Finland. Of those who completed the Stressful Life Events scale and the Stress of Daily Activities scale, 1470 and 1882, respectively, later had cancer and were included in the analysis, covering 23 years of follow-up between 1982 and 2004. In Cox regression analysis, the multivariate hazard ratio (HR) was 0.99 (95% confidence interval [CI], 0.96-1.01) for total number of life events and the HR for the life change score was 0.99 (95% CI, 0.95-1.03). Further, the HR was 0.92 (95% CI, 0.69-1.22) for severe daily stress. Overall, the results of the current study do not support the hypothesis that stress reduces cancer survival. (C) 2011 Elsevier Ltd. All rights reserved. |
| Databáze: | OpenAIRE |
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