Management of Chronic Childhood Immune Thrombocytopenic Purpura: AIEOP Consensus Guidelines
| Autor: | De Mattia D, Del Vecchio GC, Russo G, De Santis A, Ramenghi U, Notarangelo L, Jankovic M, Molinari AC, Zecca M, Nobili B, Giordano P, AIEOP ITP Study Group, Acquaviva A, Amendola G, Baronci C, Binda S, Bisogno G, Bussetti C, Ciliberti A, Citterio M, Del Principe D, Farruggia P, Ladogana S, Magro S, Masera G, Menichelli A, Nardi M, Parodi E, Tucci F, Vimercati C., PESSION, ANDREA |
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| Přispěvatelé: | DE MATTIA, D, DEL VECCHIO, Gc, Russo, G, DE SANTIS, A, Ramenghi, U, Notarangelo, L, Jankovic, M, Molinari, Ac, Zecca, M, Nobili, Bruno, Giordano, P, AIEOP ITP STUDY, Group, De Mattia D, Del Vecchio GC, Russo G, De Santis A, Ramenghi U, Notarangelo L, Jankovic M, Molinari AC, Zecca M, Nobili B, Giordano P, AIEOP-ITP Study Group,Acquaviva A, Amendola G, Baronci C, Binda S, Bisogno G, Bussetti C, Ciliberti A, Citterio M, Del Principe D, Farruggia P, Ladogana S, Magro S, Masera G, Menichelli A, Nardi M, Parodi E, Pession A, Tucci F, Vimercati C. |
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Pediatrics
medicine.medical_specialty Platelet count Adolescent Consensus Development Conferences as Topic Prednisolone Rho(D) Immune Globulin medicine.medical_treatment conta piastrinica Splenectomy Platelet Transfusion management of pediatric thrombocytopenia idiopathic thrombocytopenic purpura platelet count trattamento della piastrinopenia pediatrica porpora trombocitopenica idiopatica Immune system immune system diseases hemic and lymphatic diseases medicine Pediatric thrombocytopenia Humans Platelet Idiopathic thrombocytopenic purpura Management of pediatric thrombocytopenia Thrombocytopenia Child Purpura Thrombocytopenic Idiopathic biology business.industry Immunoglobulins Intravenous Infant Hematology General Medicine medicine.disease Thrombocytopenic purpura Purpura Chronic disease Platelet transfusion Child Preschool Chronic Disease biology.protein Antibody medicine.symptom business Idiopathic thrombocytopenic purpura Management of pediatric thrombocytopenia Pediatric thrombocytopenia Platelet count Thrombocytopenia |
| Popis: | Background/Objective: The management of chronic childhood idiopathic thrombocytopenic purpura (ITP) is distinct from acute ITP. Similar to the publication on acute ITP guidelines, the AIEOP (Associazione Italiana di Ematologia e Oncologia Pediatrica) considered it appropriate to develop consensus guidelines for chronic childhood ITP to provide useful and shared information for physicians, healthcare professionals, parents and patients. Design/Methods: A preliminary, evidence-based document issued by a select group of AIEOP pediatric hematologists was discussed, modified and approved during a Consensus Conference according to procedures previously validated by the AIEOP Board. Results: The guidelines give prominence to the periodical reevaluation of all the etiological hypotheses of thrombocytopenia in relation to its clinical condition. The majority of chronic ITP children do not require treatment, especially if bleeding is absent or minimal. The treatment decision depends on several factors other than the platelet count, and treatment options are suggested in relation to the therapeutic scenarios. Recommendations are given regarding support for surgery, particular hemorrhagic conditions, daily activities/sports, as well as for vaccines and drugs. Experimental treatments are also discussed. |
| Databáze: | OpenAIRE |
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