Low-Grade B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue Arising in the Thymus
| Autor: | Bruce J. Addis, Cacilia Tang, Peter G. Isaacson, John K.C. Chan |
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| Rok vydání: | 1990 |
| Předmět: |
Male
Pathology medicine.medical_specialty Lymphoma Lymphoid Tissue Population Salivary Gland Diseases Biology Sialadenitis Pathology and Forensic Medicine Diagnosis Differential immune system diseases hemic and lymphatic diseases medicine Humans education Thymic Lymphoma B-Lymphocytes education.field_of_study Mucous Membrane Staining and Labeling Myoepithelial cell MALT lymphoma Thymus Neoplasms Middle Aged medicine.disease Immunohistochemistry Lymphatic system Female Surgery Anatomy Mucosa-associated lymphoid tissue |
| Zdroj: | The American Journal of Surgical Pathology. 14:342-351 |
| ISSN: | 0147-5185 |
| DOI: | 10.1097/00000478-199004000-00005 |
| Popis: | We describe two cases of primary low-grade B-cell lymphoma of the thymus that showed histological features of low-grade B-cell lymphoma arising in mucosa-associated lymphoid tissue (MALT). The appearances most closely resembled MALT lymphoma arising in myoepithelial sialadenitis (MESA). In both cases, the tumor was excised. In one case, there has been no recurrence in 4 years of follow-up without further treatment; in the second case, the tumor has involved an axillary lymph node. Immunohistochemistry showed light-chain restriction in both cases, and the B-cell phenotype was similar to that previously described in MALT lymphomas. The occurrence of MALT lymphoma in the thymus is consistent with the presence of mucosal structures (Hassall's corpuscles) and with recent descriptions of a native B-cell population in this organ. The relationship of this previously undescribed thymic low-grade B-cell MALT lymphoma arising in the thymus has not yet been clarified. |
| Databáze: | OpenAIRE |
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