Clinical and Etiological Aspects of Gynecomastia in Adult Males: A Multicenter Study

Autor: Pablo Knoblovits, Jorge Stewart Usher, N. Pacenza, S. Aszpis, Sergio Iturrieta, Silvia Gottlieb, Sebastián Matías Suárez, Miguel Vásquez Cayoja, Pablo R. Costanzo, Uriel Marcelo Pragier, Rodolfo Rey
Rok vydání: 2018
Předmět:
Male
Pediatrics
Breast pain
lcsh:Medicine
Medicina Clínica
Disease
Overweight
0302 clinical medicine
Pregnancy
Endocrinología y Metabolismo
purl.org/becyt/ford/3.2 [https]
Medicine
030212 general & internal medicine
Andrology
Young adult
skin and connective tissue diseases
Aged
80 and over
General Medicine
Middle Aged
Gynecomastia
Androgens
purl.org/becyt/ford/3 [https]
Female
medicine.symptom
Research Article
Adult
medicine.medical_specialty
CIENCIAS MÉDICAS Y DE LA SALUD
Article Subject
Adolescent
030209 endocrinology & metabolism
General Biochemistry
Genetics and Molecular Biology
Young Adult
03 medical and health sciences
Humans
Aged
Retrospective Studies
General Immunology and Microbiology
business.industry
Hypogonadism
lcsh:R
Estrogens
Retrospective cohort study
Luteinizing Hormone
medicine.disease
Cross-Sectional Studies
Etiology
Gyencomastia
business
Zdroj: BioMed Research International
BioMed Research International, Vol 2018 (2018)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
ISSN: 2314-6141
2314-6133
DOI: 10.1155/2018/8364824
Popis: Objectives. To evaluate the characteristics of presentation, biochemical profile, and etiology of gynecomastia in adults. Methods. Medical records of 237 men aged 18-85 years with gynecomastia were evaluated. Results. Highest prevalence of gynecomastia was observed between 21 and 30 years (n = 74; 31.2%). The most common presenting complaints were aesthetic concerns (62.8%) and breast pain (51.2%). 25.3% of the subjects had a history of pubertal gynecomastia. 56.5% had bilateral gynecomastia. 39.9% were overweight and 22.8% were obese. The etiology could not be identified in 45.1% of the cases; the most frequent identified causes were anabolic steroids consumption (13.9%), hypogonadism (11.1%), and use of pharmaceutical drugs (7.8%). Patients with bilateral gynecomastia had a longer history of disease, higher BMI, and lower testosterone levels. Conclusions. Patients with gynecomastia presented more often with aesthetic concerns and secondarily with breast pain. The most frequent final diagnosis was idiopathic gynecomastia, whereas the most frequent identified etiologies were anabolic steroids consumption, hypogonadism, and use of pharmaceutical drugs. Despite the low frequency of etiologies such as thyroid dysfunction or adrenal carcinoma, we emphasize the importance of a thorough assessment of the patient, as gynecomastia may be the tip of the iceberg for the diagnosis of treatable diseases. Fil: Costanzo, Pablo René. Hospital Italiano; Argentina Fil: Pacenza, Néstor Antonio. Unidad Asistencial “Dr. Cesar Milstein”,; Argentina. Centro de Endocrinolog´ıa y Diabetes “Dr. Raul Gutman”; Argentina Fil: Aszpis, Sergio Mario. Ciudad Autónoma de Buenos Aires. Hospital General de Agudos "Carlos G. Durand"; Argentina Fil: Suárez, Sebastián Matías. Hospital Italiano; Argentina Fil: Pragier, Uriel Marcelo. Complejo Medico Churruca Visca; Argentina Fil: Usher, Jorge Guillermo Stewart. Centro Medico Haedo; Argentina Fil: Vásquez Cayoja, Miguel. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina Fil: Iturrieta, Sergio. Ciudad Autónoma de Buenos Aires. Hospital General de Agudos "Carlos G. Durand"; Argentina Fil: Gottlieb, Silvia Elisa. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas "Dr. César Bergada". Gobierno de la Ciudad de Buenos Aires. Centro de Investigaciones Endocrinológicas "Dr. César Bergada". Fundación de Endocrinología Infantil. Centro de Investigaciones Endocrinológicas "Dr. César Bergada"; Argentina Fil: Rey, Rodolfo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas "Dr. César Bergada". Gobierno de la Ciudad de Buenos Aires. Centro de Investigaciones Endocrinológicas "Dr. César Bergada". Fundación de Endocrinología Infantil. Centro de Investigaciones Endocrinológicas "Dr. César Bergada"; Argentina Fil: Knoblovits, Pablo. Hospital Italiano; Argentina
Databáze: OpenAIRE
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