A scoping review of cost-effectiveness of screening and treatment for latent tuberculosis infection in migrants from high-incidence countries

Autor: Zammarchi, Lorenzo, Casadei, Gianluigi, Strohmeyer, Marianne, Bartalesi, Filippo, Liendo, Carola, Matteelli, Alberto, Bonati, Maurizio, Gotuzzo, Eduardo, Bartoloni, Alessandro, Pandolfini, Chiara, Severino, Francesca, Confalonieri, Valeria, Tognoni, Gianni, Bisoffi, Zeno, Buonfrate, Dora, Angheben, Andrea, Albonico, Marco, Muñoz, Jose, Requena Mendez, Ana, Roura, Maria, Ventura, Laia, Pool, Robert, Pell, Christopher, Hardon, Anita, Chiodini, Peter, Moreira, Juan, Anselmi, Mariella, Sempértegui, Roberto, Mena, Maria Alejandra, Garcia, Héctor H., Bustos, Javier, Santivañez, Saul, Torrico, Faustino, Lozano, Daniel, Cabrera, Teresa Hinojosa, Morón, Javier Ochoa, Abaporicuellar, Ignacio, Suarez, Jaime Amorós, Chumirayrojas, Guido, Nicoletti, Alessandra, Bruno, Elisa
Jazyk: angličtina
Předmět:
Male
Communicable Diseases
Cost-Benefit Analysis
Dental Care
Female
Humans
Incidence
Interferon-gamma Release Tests
Latent Tuberculosis
Mass Screening
Tuberculin Test
Tuberculosis
Transients and Migrants
Health Policy
medicine.medical_specialty
Tuberculin Test/economics
Cost effectiveness
Interferon gamma release assay
MEDLINE
03 medical and health sciences
0302 clinical medicine
purl.org/pe-repo/ocde/ford#3.03.02 [https]
Environmental health
Medicine
030212 general & internal medicine
Mass screening
Mass Screening/economics
Latent tuberculosis
business.industry
Incidence (epidemiology)
Public health
medicine.disease
bacterial infections and mycoses
Interferon-gamma Release Tests/economics
3. Good health
Surgery
030228 respiratory system
Tuberculosis/epidemiology
Latent Tuberculosis/diagnosis/drug therapy
business
Research Article
Zdroj: BMC Health Services Research
ISSN: 1472-6963
DOI: 10.1186/s12913-015-1045-3
Popis: Background In low-incidence countries, most tuberculosis (TB) cases occur among migrants and are caused by reactivation of latent tuberculosis infection (LTBI) acquired in the country of origin. Diagnosis and treatment of LTBI are rarely implemented to reduce the burden of TB in immigrants, partly because the cost-effectiveness profile of this intervention is uncertain. The objective of this research is to perform a review of the literature to assess the cost-effectiveness of LTBI diagnosis and treatment strategies in migrants. Methods Scoping review of economic evaluations on LTBI screening strategies for migrants was carried out in Medline. Results Nine studies met the inclusion criteria. LTBI screening was cost-effective according to seven studies. Findings of four studies support interferon gamma release assay as the most cost-effective test for LTBI screening in migrants. Two studies found that LTBI screening is cost-effective only if carried out in immigrants who are contacts of active TB cases. Discussion and Conclusions Our findings support the cost-effectiveness of LTBI diagnostic and treatment strategies in migrants especially if they are focused on young subjects from high incidence countries. These strategies could represent and adjunctive and synergistic tool to achieve the ambitious aim of TB elimination. Electronic supplementary material The online version of this article (doi:10.1186/s12913-015-1045-3) contains supplementary material, which is available to authorized users.
Databáze: OpenAIRE