Isolation of the hemeoxygenase-1 inducer from rice-derived peptide

Autor: Kayoko, Kawakami, Chie, Moritani, Tadashi, Hatanaka, Seiji, Tsuboi
Rok vydání: 2022
Předmět:
Zdroj: Journal of Clinical Biochemistry and Nutrition. 71:41-47
ISSN: 1880-5086
0912-0009
Popis: Bioactive peptides with various health benefits have been reported from rice protein hydrolysates. We previously showed that rice-derived peptides (RP) increased intracellular glutathione levels and induced the expression of γ-glutamylcysteine synthetase, which is regulated by nuclear transcription factor-erythroid 2-related factor 2 (Nrf2). Heme oxygenase-1 (HO-1) is an important Nrf2 downstream antioxidant enzyme that protects against oxidative stress. This study aimed to investigate the protective effects of RP on hydrogen peroxide (H
Databáze: OpenAIRE