Catecholamines and Renal Water Excretion
| Autor: | Robert W. Schrier, Tomas Berl, Keith M. McDonald, Judith A. Harbottle |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
medicine.medical_specialty
Vasopressin Baroreceptor Vasopressins Blood Pressure Stimulation Kidney Norepinephrine (medication) Norepinephrine Dogs Parasympathetic Nervous System In vivo Internal medicine Cyclic AMP Animals Humans Medicine Cyclic GMP business.industry Isoproterenol Water General Medicine Water excretion Autonomic nervous system Endocrinology Nephrology Pituitary Gland business medicine.drug |
| Zdroj: | Nephron. 15:186-196 |
| ISSN: | 1423-0186 0028-2766 |
| Popis: | The in vivo mechanisms whereby systemic alpha- and beta-adrenergic stimulation exert opposing effects on renal water excretion are reviewed. An extrarenal mechanism is suggested since the effect of intravenous infusion of norepinephrine or isoproterenol on water excretion cannot be mimicked by the intrarenal administration of these agents. A ROLE OF VASOPRESSIN IS IMPLICATED SINCE NEITHER MAN NOR DOG WITHOUT A PITUITARY SOURCE OF VASOPRESSIN DEMONSTRATE THE SAME EFFECT OF CATECHOLAMINES ON WATER EXCRETION AS OBSERVED IN INTACT MAN AND DOG. Evidence also is presented that systemic alpha- and beta-adrenergic stimulation affect vasopressin release primarily by altering baroreceptor tone. The potential role of the autonomic nervous system in mediating other nonosmotic stimuli for vasopressin is discussed. |
| Databáze: | OpenAIRE |
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