The role of tryptophan in don‐induced feed rejection
Autor: | B. A. Rotter, B. K. Thompson, D. B. Prelusky |
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Rok vydání: | 1996 |
Předmět: |
Male
Fusarium medicine.medical_specialty Ratón Administration Oral Weight Gain Mice chemistry.chemical_compound Vomitoxin Internal medicine medicine Animals Chromatography High Pressure Liquid Brain Chemistry chemistry.chemical_classification Mice Inbred ICR Dose-Response Relationship Drug biology fungi Tryptophan food and beverages Drug Synergism Feeding Behavior General Medicine biology.organism_classification Pollution Amino acid Endocrinology chemistry Toxicity Serotonin medicine.symptom Trichothecenes Weight gain Food Science |
Zdroj: | Journal of Environmental Science and Health, Part B. 31:1279-1288 |
ISSN: | 1532-4109 0360-1234 |
Popis: | Deoxynivalenol (DON, vomitoxin) commonly produced by Fusarium fungi can alter feeding behaviour of pigs and other farm animals. The effects of dietary tryptophan (TRP, precursor of brain amine serotonin) in combination with DON were examined in mice to determine if TRP can modulate DON toxicity. Results indicated that brain TRP can be influenced by dietary TRP, but no evidence of TRP potentiating DON toxicity was observed. Higher TRP levels likely induced amino acid imbalance leading to weight gain suppression. |
Databáze: | OpenAIRE |
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