Extramedullary Plasmacytoma of the Small Intestine: A Case Report
| Autor: | Yoshihumi Niitsu, Taiki Masuda, Masako Suzuki, Takeo Ogino, Takeshi Machida, Masatoshi Kawamura, Sotaro Kanno, Nobuyuki Sakamoto, Yukiyoshi Esaki, Junjiro Katsurada, Takeharu Kawamura, Naoyuki Kobayashi, Shinji Takahashi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
Chemotherapy
Gastrointestinal tract Pathology medicine.medical_specialty medicine.medical_treatment Russell bodies cyclin D1 General Medicine Biology Swollen lymph nodes Small intestine medicine.anatomical_structure Subserosa medicine Lymph medicine.symptom Mesentery small intestine extramedullary plasmacytoma |
| Zdroj: | The Kitakanto medical journal = 北関東医学. 57(3):251-254 |
| ISSN: | 1343-2826 |
| Popis: | Extramedullary plasmacytoma (EMP) of the gastrointestinal tract is an uncommon-type of neoplasms.\nThis report describes a case of EMP in the small intestine. A 78-year-old male,with abdominal\ndiscomfort and vomiting, was found to have a 7-cm sized tumor of the small intestine and swollen\nlymph nodes. He underwent resection of the bowel and lymph nodes. Histological examination of the\nresected specimens revealed compact tumor cells from mucosa to subserosa and infiltrate into the fat tissue\nof the mesentery and the lymph nodes. Pathological examination of the resected specimen revealed\nplasma cell-like round cells, Dutcher bodies, and Russell bodies. Immunohistochemical examination\nshowed that the cytoplasm of the tumor cells were positive for CD138 and the nuclei were positive for\ncyclin D1. Four months after surgical resection, the patient had recurrence of tumor cells in the\npara-aortic lymph nodes and lumbar vertebrae. Chemotherapy treatment was ineffective. Surgical\nresection followed by chemotherapy is thought to be effective in the case of intestinal obstruction,\nalthough there is a possibility of devastation which is resistant to chemotherapy. We propose that tumor\ncells positive for cyclin D1 may play a key role in devastation and could be a useful indicator of\nprognosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|