Supplementary Table S5 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas

Autor: J. William Harbour, Stefan Kurtenbach, Christina L. Decatur, Karam A. Alawa, Louie Z. Cai, Parker L. Bussies, Jeffim N. Kuznetsov, Matthew G. Field
Rok vydání: 2023
Popis: BAP1KDvsWT_HyperMethyl: All significantly hypermethylated probes (FDR < 0.05) with an absolute value (log2(RNA fold change)) > 1 and absolute value (methylation Delta Beta value) > 0.01 in BAP1KDvsWT 92.1 and Mel202 cells. BAP1KDvsWT_HypoMethyl: All significantly hypomethylated probes (FDR < 0.05) with an absolute value (log2(RNA fold change)) > 1 and absolute value (methylation Delta Beta value) > 0.01 in BAP1KDvsWT 92.1 and Mel202 cells. BAP1KD_HyperMeth_ChrLoc: Chromosomal loci enriched (FDR < 0.05) for top 1000 hypermethylated genes in BAP1KDvsWT 92.1 and Mel202 cells. BAP1KD_HypoMeth_ChrLoc: Chromosomal loci enriched (FDR < 0.05) for top 1000 hypomethylated genes in BAP1KDvsWT 92.1 and Mel202 cells. BAP1KD_HyperMeth_KEGG_REACTOME: Functional (KEGG and REACTOME) pathways enriched (FDR < 0.05) for top 1000 hypermethylated genes in BAP1KDvsWT 92.1 and Mel202 cells. BAP1KD_HypoMeth_KEGG_REACTOME: Functional (KEGG and REACTOME) pathways enriched (FDR < 0.05) for for top 1000 hypomethylated genes in BAP1KDvsWT 92.1 and Mel202 cells.
Databáze: OpenAIRE