Genetic characterization of avian influenza viruses isolated in Israel during 2000–2006
| Autor: | Michael Pirak, Irit Davidson, Y Tendler, A. Panshin, Maricarmen García, Shimon Perk, Shimon Pokamunski, Caroline Banet-Noach, Sagit Nagar, Natalia Golender |
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| Rok vydání: | 2008 |
| Předmět: |
Turkeys
Asia viruses animal diseases Molecular Sequence Data Neuraminidase Hemagglutinin (influenza) Hemagglutinin Glycoproteins Influenza Virus Chick Embryo medicine.disease_cause H5N1 genetic structure Disease Outbreaks Viral Proteins Virology Influenza A Virus H9N2 Subtype Genetics medicine Animals Israel Molecular Biology Gene Phylogeny Polymerase Influenza A Virus H5N1 Subtype biology Phylogenetic tree virus diseases General Medicine RNA-Dependent RNA Polymerase Influenza A virus subtype H5N1 Nucleoprotein Europe Animals Domestic Influenza in Birds biology.protein Chickens |
| Zdroj: | Virus Genes. 37:289-297 |
| ISSN: | 1572-994X 0920-8569 |
| DOI: | 10.1007/s11262-008-0272-7 |
| Popis: | Our aim was to establish the phylogenetic and genetic relationships among avian influenza viruses (AIV) recently isolated from poultry in Israel. During this study we analyzed complete nucleotide sequences of two envelope (hemagglutinin and neuraminidase) and six internal genes (polymerase B1, polymerase B2, polymerase A, nucleoprotein, nonstructural, and matrix) of 29 selected H9N2 and six internal genes of five H5N1 viruses isolated in Israel during 2000-2006. Comparative genetic and phylogenetic analyses of these sequences revealed that the local H5N1 viruses are closely related to H5N1 viruses isolated in European, Asian, and Middle Eastern countries in 2005-2006. The H9N2 Israeli isolates, together with viruses isolated in Jordan and Saudi Arabia formed a single group. Our data support the claim that during recent years a new endemic focus of H9N2 has been formed in the Middle East. The introduction of H5N1 and co-circulation of these two subtypes of AIV in this region may augment the risk of potentially pandemic strains emergence. |
| Databáze: | OpenAIRE |
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