Protein lysine acetylation in bacteria: Current state of the art
| Autor: | Tassadit Ouidir, Julie Hardouin, Takfarinas Kentache |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Proteomics Lysine Virulence Biology complex mixtures Biochemistry 03 medical and health sciences Bacterial Proteins Protein lysine acetylation Humans Molecular Biology Cellular metabolism Bacteria Acetylation biology.organism_classification Metabolic pathway 030104 developmental biology bacteria Protein Processing Post-Translational Metabolic Networks and Pathways |
| Zdroj: | Proteomics. 16(2) |
| ISSN: | 1615-9861 |
| Popis: | Post-translational modifications of proteins are key events in cellular metabolism and physiology regulation. Lysine acetylation is one of the best studied protein modifications in eukaryotes, but, until recently, ignored in bacteria. However, proteomic advances have highlighted the diversity of bacterial lysine-acetylated proteins. The current data support the implication of lysine acetylation in various metabolic pathways, adaptation and virulence. In this review, we present a broad overview of the current knowledge of lysine acetylation in bacteria. We emphasize particularly the significant contribution of proteomics in this field. |
| Databáze: | OpenAIRE |
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