Continuous Fentanyl Background Infusion Regimen Optimised by Patient-Controlled Analgesia for Acute Postoperative Pain Management: A Randomised Controlled Trial

Autor:	Sang Kee Min, Jihoon Hwang, Han Bum Joe, Yun Jeong Chae, Gang Mee Lim
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Visual analogue scale medicine.medical_treatment lcsh:Medicine fentanyl Article law.invention Fentanyl 03 medical and health sciences patient-controlled analgesia 0302 clinical medicine Patient satisfaction Randomized controlled trial 030202 anesthesiology law medicine Patient-controlled analgesia business.industry Incidence (epidemiology) lcsh:R background infusion General Medicine Regimen postoperative pain management Anesthesia Acute postoperative pain business 030217 neurology & neurosurgery medicine.drug
Zdroj:	Journal of Clinical Medicine Volume 9 Issue 1 Journal of Clinical Medicine, Vol 9, Iss 1, p 211 (2020)
ISSN:	2077-0383
DOI:	10.3390/jcm9010211
Popis:	Owing to a lack of studies investigating the effect of adjustments in fentanyl background infusion (BI) with patient-controlled analgesia (PCA) on postoperative analgesia, we evaluated three BI regimens with fentanyl PCA for acute postoperative pain management. This randomised controlled trial enrolled 105 patients, who were assigned to three parallel groups: constant rate BI of 2 mL/h (CRBI group) time-scheduled decremental BI of 6, 2 and 1 mL/h (TDBI group) and BI rates optimised to the demand of PCA (POBI group). The incidence of insufficient analgesia, visual analogue scale (VAS) pain score and side effects were evaluated. The incidence of insufficient analgesia in the post-anaesthesia care unit was lower in the TDBI and POBI groups than the CRBI group. Incidence of insufficient analgesia in the ward was lower in the POBI group than the CRBI group. Postoperative VAS scores were significantly lower in the TDBI and POBI groups for up to 4 h and 24 h, respectively, compared with the CRBI group. Side effects and infused fentanyl dose were highest in the CRBI group. Adjusting BI rate based on time or patient demands could improve postoperative analgesia and reduce side effects. Compared to a constant BI rate, PCA-optimised BI achieved higher patient satisfaction.
Databáze:	OpenAIRE
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