Thermal intravascular photoacoustic imaging
| Autor: | Stanislav Emelianov, Bo Wang |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Pathology
medicine.medical_specialty Materials science ocis:(170.6935) Tissue characterization Photoacoustic imaging in biomedicine 030204 cardiovascular system & hematology Photoacoustic Imaging and Spectroscopy 01 natural sciences 010309 optics 03 medical and health sciences 0302 clinical medicine 0103 physical sciences medicine ocis:(110.7170) Ultrasound Tissue specific ocis:(170.0170) Medical optics and biotechnology ocis:(110.5120) Photoacoustic imaging business.industry Ultrasound Rabbit aorta Tissue characterization Atomic and Molecular Physics and Optics Imaging technique business Tissue composition Ex vivo Biotechnology Biomedical engineering |
| Zdroj: | Biomedical Optics Express |
| ISSN: | 2156-7085 |
| Popis: | Intravascular photoacoustics (IVPA)—a minimally invasive imaging technique with contrast related to optical absorption properties of tissue, can be used to visualize atherosclerotic plaques. However, the amplitude of photoacoustic signals is also related to a temperature dependent, tissue specific parameter—the Gruneisen parameter. Therefore, photoacoustic signals measured at different temperatures may reveal information about tissue composition. In this study, thermal IVPA (tIVPA) imaging was introduced. The imaging studies were performed using an ex vivo atherosclerotic rabbit aorta. Temperature dependent photoacoustic responses from lipid in plaques and lipid in periadventitial tissue were different, thus allowing tIVPA images to delineate the location of lipid-rich plaques. The results indicate that tIVPA imaging has a potential to characterize tissue composition in atherosclerotic vessels. |
| Databáze: | OpenAIRE |
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