Circulation of third-generation cephalosporin resistant Salmonella Typhi in Mumbai, India

Autor:	Stephen Baker, Silvia Argimón, Varun Shamanna, Ravikumar Kadahalli Lingegowda, Mihir Kekre, David M. Aanensen, Ashwini Kodlipet Vasanth, Anurag Kumar Bari, Geetha Nagaraj, Akshatha Prasanna, Aruna Poojary, Sravani Darmavaram, Anthony Underwood
Rok vydání:	2021
Předmět:	Microbiology (medical) medicine.drug_class Cephalosporin India Context (language use) Microbial Sensitivity Tests Biology Salmonella typhi Typhoid fever beta-Lactamases Microbiology Esbl gene Plasmid Drug Resistance Bacterial medicine Humans Gene business.industry biochemical phenomena metabolism and nutrition medicine.disease bacterial infections and mycoses Fluoroquinolone resistance Third generation Anti-Bacterial Agents Cephalosporins Triple mutant Infectious Diseases business Fluoroquinolones
DOI:	10.1101/2021.08.25.457312
Popis:	We report the persistent circulation of third-generation cephalosporin resistant Salmonella Typhi in Mumbai, linked to the acquisition and maintenance of a previously characterized IncX3 plasmid carrying the ESBL gene blaSHV-12 and the fluoroquinolone resistance gene qnrB7 in the genetic context of a triple mutant also associated with fluoroquinolone resistance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0516c91d9e08b6ac31dfd89c55707e62 https://doi.org/10.1101/2021.08.25.457312 Zobrazit plný text záznamu