Clinical Outcomes after Oat Beta-Glucans Dietary Treatment in Gastritis Patients
| Autor: | Małgorzata Jałosińska, Sylwia Gudej, Ewa Lange, Michał Oczkowski, Katarzyna Dziendzikowska, Joanna Harasym, Rafał Filip, Małgorzata Juszczak, Joanna Gromadzka-Ostrowska, Jacek Wilczak |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty beta-Glucans Antioxidant Avena medicine.medical_treatment short-chain fatty acids Chronic gastritis Disease Gastroenterology Article Feces Young Adult chemistry.chemical_compound Double-Blind Method Lactobacillales Internal medicine Humans Medicine oat beta-glucan TX341-641 Beta (finance) Aged Nutrition and Dietetics biology business.industry Nutrition. Foods and food supply Osmolar Concentration gastritis food and beverages Middle Aged Fatty Acids Volatile medicine.disease biology.organism_classification antioxidant properties Lactic acid inflammatory process Treatment Outcome chemistry Chronic Disease Female Gastritis medicine.symptom business prebiotics Bacteria Food Science |
| Zdroj: | Nutrients, Vol 13, Iss 2791, p 2791 (2021) Nutrients Volume 13 Issue 8 |
| ISSN: | 2072-6643 |
| Popis: | The prevalence of gastritis in humans is constantly growing and a prediction of an increase in this health problem is observed in many countries. For this reason, effective dietary therapies are sought that can alleviate the course of this disease. The objective of this study was to determine the effect of chemically pure oat beta-glucan preparations with different molar masses, low or high, used for 30 days in patients with histologically diagnosed chronic gastritis. The study enrolled 48 people of both genders of different ages recruited from 129 patients with a gastritis diagnosis. Before and after the therapy, hematological, biochemical, immunological and redox balance parameters were determined in the blood and the number of lactic acid bacteria and SCFA concentrations in the feces. Our results demonstrated a beneficial effect of oat beta-glucans with high molar mass in chronic gastritis in humans, resulting in reduced mucosal damage and healthy changes in SCFA fecal concentration and peripheral blood serum glutathione metabolism and antioxidant defense parameters. This fraction of a highly purified oat beta-glucan is safe for humans. Its action is effective after 30 days of use, which sheds new light on the nutritional treatment of chronic gastritis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|