Diagnosis of acute ischemic stroke based on time-to-peak and diffusion-weighted magnetic resonance imaging
| Autor: | Hirofumi Hiyama, Keisuke Maruyama, Masafumi Izumi, Shigeo Sora, Keisuke Ueki, Tsuneyoshi Eguchi |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Male
medicine.medical_specialty Hemodynamics Brain Ischemia Occlusion medicine Humans Stroke Acute ischemic stroke Aged Aged 80 and over medicine.diagnostic_test business.industry Magnetic resonance imaging Middle Aged medicine.disease Trunk Magnetic Resonance Imaging Acute Disease Time to peak Surgery Female Neurology (clinical) Radiology business Nuclear medicine Cerebral angiography |
| Zdroj: | Neurologia medico-chirurgica. 42(7) |
| ISSN: | 0470-8105 |
| Popis: | Rapid and accurate diagnosis of the hemodynamics of the brain is essential for the treatment of acute ischemic stroke. This study investigated whether time-to-peak and diffusion-weighted magnetic resonance (MR) imaging are useful for predicting the course of stroke. Fourteen patients with non-lacunar acute ischemic stroke underwent emergent MR imaging within 24 hours from the onset followed by cerebral angiography and xenon-enhanced computed tomography (CT). Serial CT was obtained to monitor changes in the size and nature of the infarct. Volumes of the abnormal lesions demonstrated on time-to-peak (VT) or diffusion-weighted (VD) images were measured, and the ratio of VT to VD was calculated. Based on this ratio, patients were classified into three groups: Group 1 (VT/VD 0.5-1.5, n = 9), Group 2 (VT/VD > 1.5, n = 3), and Group 3 (VT/VD < 0.5, n = 2). The size of the infarct detected as a low-density area on serial CT scans did not change significantly throughout the course in Group 1 patients, but showed enlargement in all three patients in Group 2. Two patients in Group 3 had major trunk occlusion followed by spontaneous reperfusion, and both developed hemorrhagic transformation. Our study showed that classification of ischemic stroke based on the VT/VD ratio was predictive of the time course of the infarct, and may be useful in selecting the initial therapeutic procedure immediately after the onset of stroke. |
| Databáze: | OpenAIRE |
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