Recovery from cisplatin-induced ototoxicity: a case report and review
| Autor: | Mai Thy Truong, Jody Winzelberg, Kay W. Chang |
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| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Hearing loss Hearing Loss Sensorineural Antineoplastic Agents Bone Neoplasms Audiology Severity of Illness Index Tinnitus Ototoxicity otorhinolaryngologic diseases Medicine Humans Dosing Cisplatin Osteosarcoma business.industry General Medicine Recovery of Function Humerus medicine.disease Chemotherapy regimen Cochlea Otorhinolaryngology Acoustic Stimulation Concomitant Anesthesia Pediatrics Perinatology and Child Health Sensorineural hearing loss medicine.symptom business medicine.drug |
| Zdroj: | International journal of pediatric otorhinolaryngology. 71(10) |
| ISSN: | 0165-5876 |
| Popis: | We present a pediatric case report of cisplatin-induced ototoxicity with subsequent recovery. The patient experienced tinnitus and fluctuating mild high-frequency sensorineural hearing loss (SNHL) with a concomitant decrease in distortion product otoacoustic emissions (DPOAE). There was recovery of hearing loss and return of DPOAE at 1 year after completion of cisplatin therapy. Reports of recovery from cisplatin-induced ototoxicity in humans are limited in the literature, especially in the pediatric population. A review of cisplatin ototoxicity and mechanisms of recovery are discussed, with an emphasis on the particular chemotherapy regimen and dosing schedule in this case, given at 4-11 week intervals. |
| Databáze: | OpenAIRE |
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