Population structure of a vector of human diseases: Aedes aegypti in its ancestral range, Africa

Autor: Basile Kamgang, Carla A. Sousa, Martin N. Mayanja, Gilbert Le Goff, Panayiota Kotsakiozi, Arlete D. Troco, João Pinto, Athanase Badolo, Andrea Gloria-Soria, Christophe Paupy, Julius J. Lutwama, Diego Ayala, Benjamin R. Evans, Jeffrey R. Powell
Přispěvatelé: Yale University [New Haven], Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), International Network for the Sequencing of resPIRratory vIrusEs (INSPIRE), Diversity, ecology, evolution & Adaptation of arthropod vectors (MIVEGEC-DEEVA), Evolution des Systèmes Vectoriels (ESV), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Centre International de Recherches Médicales de Franceville (CIRMF), Université Joseph Ki-Zerbo [Ouagadougou] (UJZK), Universidade Nova de Lisboa = NOVA University Lisbon (NOVA), Centre international de recherches médicales de Franceville (CIRMF), Organisation Mondiale de la Santé (OMS), Université de Ouagadougou, Universidade Nova de Lisboa (NOVA), Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Ecology and Evolution
Ecology and Evolution, 2018, 8 (16), pp.7835-7848. ⟨10.1002/ece3.4278⟩
Ecology and Evolution, Wiley Open Access, 2018, 8 (16), pp.7835-7848. ⟨10.1002/ece3.4278⟩
Ecology and Evolution, Vol 8, Iss 16, Pp 7835-7848 (2018)
ISSN: 2045-7758
Popis: International audience; Aedes aegypti, the major vector of dengue, yellow fever, chikungunya, and Zika viruses , remains of great medical and public health concern. There is little doubt that the ancestral home of the species is Africa. This mosquito invaded the New World 400-500 years ago and later, Asia. However, little is known about the genetic structure and history of Ae. aegypti across Africa, as well as the possible origin(s) of the New World invasion. Here, we use ~17,000 genome-wide single nucleotide polymor-phisms (SNPs) to characterize a heretofore undocumented complex picture of this mosquito across its ancestral range in Africa. We find signatures of human-assisted migrations, connectivity across long distances in sylvan populations, and of local ad-mixture between domestic and sylvan populations. Finally, through a phylogenetic analysis combined with the genetic structure analyses, we suggest West Africa and especially Angola as the source of the New World's invasion, a scenario that fits well with the historic record of 16th-century slave trade between Africa and Americas.
Databáze: OpenAIRE
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