Methylthioadenosine nucleosidase in normal and dystrophic human muscle
| Autor: | Nirmal C. Kar, Carl M. Pearson |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Adenosine
Thionucleosides Myositis Muscles Biochemistry (medical) Clinical Biochemistry Skeletal muscle Neuromuscular Diseases General Medicine Biology medicine.disease Biochemistry Polymyositis Muscular Dystrophies medicine.anatomical_structure Purine-Nucleoside Phosphorylase Human muscle Methylthioadenosine nucleosidase medicine Humans In patient Pentosyltransferases Adenosine metabolism |
| Zdroj: | Clinica Chimica Acta. 108:465-468 |
| ISSN: | 0009-8981 |
| DOI: | 10.1016/0009-8981(80)90354-x |
| Popis: | Human skeletal muscle homogenate was found to contain a nucleosidase that catalyzes the hydrolysis of 5'-methylthioadenosine, a known inhibitor of many methyl transfer reactions. When the levels of methylthioadenosine nucleosidase in muscle of patients were compared with those of controls, no significant alterations in its activity were noted in patients with various forms of muscular dystrophies, polymyositis and certain denervating diseases. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|