Malaria Temporal Variation and Modelling Using Time-Series in Sussundenga District, Mozambique
| Autor: | João Ferrão, Alberto Tungadza, Dominique Earland, Kelly M. Searle, Roberto Mendes, Anisio Novela |
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| Rok vydání: | 2021 |
| Předmět: |
Wet season
medicine.medical_specialty Health Toxicology and Mutagenesis temporal 030231 tropical medicine malaria Article modelling 03 medical and health sciences 0302 clinical medicine Sussundenga parasitic diseases Epidemiology medicine Humans 030212 general & internal medicine Autoregressive integrated moving average Malaria Falciparum Child Mozambique Under-five Incidence Incidence (epidemiology) Rural health Public Health Environmental and Occupational Health Seasonality medicine.disease Geography Child Preschool Medicine Seasons Malaria Demography |
| Zdroj: | International Journal of Environmental Research and Public Health Volume 18 Issue 11 International Journal of Environmental Research and Public Health, Vol 18, Iss 5692, p 5692 (2021) |
| ISSN: | 1660-4601 |
| DOI: | 10.3390/ijerph18115692 |
| Popis: | Malaria is one of the leading causes of morbidity and mortality in Mozambique, which has the fifth highest prevalence in the world. Sussundenga District in Manica Province has documented high P. falciparum incidence at the local rural health center (RHC). This study’s objective was to analyze the P. falciparum temporal variation and model its pattern in Sussundenga District, Mozambique. Data from weekly epidemiological bulletins (BES) was collected from 2015 to 2019 and a time-series analysis was applied. For temporal modeling, a Box-Jenkins method was used with an autoregressive integrated moving average (ARIMA). Over the study period, 372,498 cases of P. falciparum were recorded in Sussundenga. There were weekly and yearly variations in incidence overall (p < 0.001). Children under five years had decreased malaria tendency, while patients over five years had an increased tendency. The ARIMA (2,2,1) (1,1,1) 52 model presented the least Root Mean Square being the most appropriate for forecasting. The goodness of fit was 68.15% for malaria patients less than five years old and 73.2% for malaria patients over five years old. The findings indicate that cases are decreasing among individuals less than five years and are increasing slightly in those older than five years. The P. falciparum case occurrence has a weekly temporal pattern peaking during the wet season. Based on the spatial and temporal distribution using ARIMA modelling, more efficient strategies that target this seasonality can be implemented to reduce the overall malaria burden in both Sussundenga District and regionally. |
| Databáze: | OpenAIRE |
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