A STR mutation in a heteropaternal twin case
| Autor: | R. Espinheira, Burkhard Rolf, Carsten Hohoff, Teresa Ribeiro, Rui M. Brito, Bernd Brinkmann, Helena Geada |
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| Rok vydání: | 2001 |
| Předmět: |
Genetics
Male Locus (genetics) Paternity social sciences Minisatellite Repeats Biology DNA Fingerprinting eye diseases humanities Pathology and Forensic Medicine Minisatellite Heteropaternal twins Short tandem repeats Tandem Repeat Sequences Mutation Twins Dizygotic Minisatellites Microsatellite Humans Female ACTBP2 mutation Law Paternity investigation |
| Zdroj: | Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP |
| ISSN: | 0379-0738 |
| Popis: | A heteropaternal male twin case with two men being alleged fathers was investigated as requested by the Court. Up to 37 PCR-based polymorphic DNA systems were studied in this case which was complicated by a paternal ACTBP2 mutation detected in one twin. This is the first report on a STR mutation in a double paternity case where both biological fathers were indisputably identified. The STR systems enable the resolution of these complex genetic relationships even in a case where a mutation in one STR locus was encountered. |
| Databáze: | OpenAIRE |
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