Histology-tailored multidisciplinary management of primary retroperitoneal sarcomas

Autor: S. Bonvalot, C. Roland, C. Raut, C. Le Péchoux, D. Tzanis, A.M. Frezza, A. Gronchi
Rok vydání: 2023
Předmět:
Zdroj: European Journal of Surgical Oncology. 49:1061-1067
ISSN: 0748-7983
DOI: 10.1016/j.ejso.2022.05.010
Popis: Until recently, the recommendation for primary retroperitoneal sarcomas (RPS) was to perform a complete en-bloc gross excision, (neo) adjuvant treatments being options which were not validated by randomized studies, with a large discrepancy of use between centers. The heterogeneity of RPS, with their different biological behaviour, renders a homogenous therapeutic and surgical approach probably inappropriate. Recent studies, both surgical and dedicated to adjuvant treatments, allow refining these recommendations. This review summarizes recent advances and directions.
Databáze: OpenAIRE