Increased Consumption of Sulfur Amino Acids by Both Sows and Piglets Enhances the Ability of the Progeny to Adverse Effects Induced by Lipopolysaccharide

Autor: Luoyi Zhu, Ling Zhao, Jeremy Jachacz, Lv-Hui Sun, Shujun Zhang, Desheng Qi, Dolores I Batonon-Alavo, Ying Zhang, Bao-yang Xu, Li-Bao Ma
Rok vydání: 2019
Předmět:
Zdroj: Animals : an Open Access Journal from MDPI
Animals
Volume 9
Issue 12
ISSN: 2076-2615
DOI: 10.3390/ani9121048
Popis: This study determined the effects of increased consumption of sulfur amino acids (SAA), as either DL-Met or Hydroxy-Met (OH-Met), by sows and piglets on their performance and the ability of the progeny to resist a lipopolysaccharide (LPS) challenge. Thirty primiparous sows were fed a diet adequate in SAA (CON) or CON + 25% SAA, either as DL-Met or OH-Met from gestation day 85 to postnatal day 21. At 35 d old, 20 male piglets from each treatment were selected and divided into 2 groups (n = 10/treatment) for a 3 ×
2 factorial design [diets (CON, DL-Met or OH-Met) and challenge (saline or LPS)]. OH-Met and/or DL-Met supplementation increased (p &le
0.05) piglets&rsquo
body weight gain during day 0&ndash
7 and day 7&ndash
14. Sow&rsquo
s milk quality was improved in the supplemented treatments compared to the CON. The LPS challenge decreased (p &le
performance from 35 to 63 d and increased (p &le
0.05) the levels of aspartate aminotransferase, total bilirubin, IL-1&beta
IL-6, TNF-a, and malondialdehyde. Plasma albumin, total protein, total antioxidant capacity and glutathione peroxidase decreased post-challenge. The results were better with OH-Met than DL-Met. The increase of Met consumption, particularly as OH-Met increased piglets&rsquo
growth performance during the lactation phase and the challenging period.
Databáze: OpenAIRE
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