Serum FSH Levels in Coasting Programmes on the hCG Day and Their Clinical Outcomes in IVF ± ICSI Cycles
Autor: | Amanda J. Tozer, Talha Al-Shawaf, Jerome Bouaziz, Ariel Zosmer, S. Vitthala |
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Rok vydání: | 2012 |
Předmět: |
Gynecology
endocrine system medicine.medical_specialty lcsh:RC648-665 Serum fsh Article Subject Endocrine and Autonomic Systems business.industry Endocrinology Diabetes and Metabolism Clinical pregnancy Reproductive medicine Retrospective cohort study Ivf icsi lcsh:Diseases of the endocrine glands. Clinical endocrinology Fsh levels Endocrinology Clinical Study medicine Live birth business hormones hormone substitutes and hormone antagonists |
Zdroj: | International Journal of Endocrinology, Vol 2012 (2012) International Journal of Endocrinology |
ISSN: | 1687-8345 1687-8337 |
Popis: | Introduction. Coasting is the most commonly used strategy in prevention of severe OHSS. Serum FSH levels measurements during coasting may aid in optimizing the duration of coasting.Objective(s). To study live birth rates (LBRs), clinical pregnancy rates (CPRs), and optimal duration of coasting based on serum FSH levels on the hCG day.Materials and Methods.It is a retrospective study performed between 2005 and 2008 at Barts and The London Centre for Reproductive Medicine, NHS Trust, London, UK, on 349-coasted women undergoing controlled ovarian stimulation (COS) for IVF ± ICSI. The serum FSH level measurements on the hCG day during coasting programme were analysed to predict the LBR and CPR.Result(s). LBR and CPR were significantly higher when the FSH levels on the hCG day were >2.5 IU/L (LBR: 32.5%,P= 0.045 and CPR: 36.9%,P= 0.027) compared to FSH Conclusion(s). Coasting may be continued as long as either serum FSH level is > 2.5 IU/L on the hCG day without compromising the LBR and CPR or to maximum of 4 days. |
Databáze: | OpenAIRE |
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