Synergistic value of simultaneous stress dobutamine sestamibi single-photon-emission computerized tomography and echocardiography in the detection of coronary artery disease
| Autor: | Roxy Senior, C. E. Handler, Efthymios Anagnostou, B. S. Sridhara, Avijit Lahiri, Edward B. Raftery |
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| Rok vydání: | 1994 |
| Předmět: |
Male
Technetium Tc 99m Sestamibi medicine.medical_specialty chemistry.chemical_element Coronary Disease Single photon emission computerized tomography Technetium Chest pain Coronary artery disease Electrocardiography Dobutamine Internal medicine medicine.artery medicine Humans Circumflex Aged Aged 80 and over Tomography Emission-Computed Single-Photon business.industry Dobutamine stress Middle Aged Prognosis medicine.disease Logistic Models chemistry Echocardiography Right coronary artery Exercise Test Cardiology Female medicine.symptom Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | American Heart Journal. 128:713-718 |
| ISSN: | 0002-8703 |
| DOI: | 10.1016/0002-8703(94)90269-0 |
| Popis: | The relative value of exercise electrocardiography, simultaneous dobutamine technetium 99m-sestamibi (MIBI) single-photon-emission computerized tomography (SPECT), and echocardiography were evaluated for the diagnosis of coronary artery disease in patients with chest pain. Sixty-one consecutive patients underwent exercise electrocardiography and simultaneous graded dobutamine echocardiography and MIBI imaging. All patients underwent coronary arteriography. The exercise electrocardiogram was found to be a poor predictor of coronary artery disease (p not significant). Individually, MIBI SPECT and echocardiography were significantly predictive of coronary artery disease (p < 0.001). According to logistic regression analysis, the combined imaging modalities significantly increased the prediction of coronary artery disease for any vessel (p < 0.001), for multiple vessels (p < 0.001), and for the left anterior descending (p < 0.001), for right coronary artery (p < 0.001), and for left circumflex arteries (p < 0.01), compared with either MIBI SPECT or echocardiography alone. The results suggest a synergism in the detection of coronary artery disease when MIBI SPECT and echocardiography are combined during dobutamine stress. |
| Databáze: | OpenAIRE |
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