Olfactory neuroblastoma: A frontal lobe disorder and a runny nose
Autor: | Tim van Osch, Bastiaan C. Ter Meulen, Henri A.J.M. Overtoom |
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Rok vydání: | 2016 |
Předmět: |
medicine.medical_specialty
Cerebrospinal Fluid Rhinorrhea Nose Neoplasms Esthesioneuroblastoma Olfactory Urinary incontinence 03 medical and health sciences 0302 clinical medicine Fatal Outcome Esthesioneuroblastoma medicine Humans Nose rhinorrhea Olfactory Neuroblastoma business.industry Middle Aged medicine.disease Frontal lobe disorder Frontal Lobe Expressive aphasia medicine.anatomical_structure Frontal lobe 030220 oncology & carcinogenesis Female Neurology (clinical) Radiology medicine.symptom Nasal Cavity business 030215 immunology |
Zdroj: | Neurology. 86(13) |
ISSN: | 1526-632X |
Popis: | A 56-year-old woman presented with progressive apathy, expressive aphasia, urinary incontinence, and a subtle right hemiparesis. She had a recent history of clear rhinorrhea and frequent nosebleeds. CT and MRI scan revealed a large mass in the left nasal cavity extending into the frontal lobe (figure 1). The diagnosis of olfactory neuroblastoma was confirmed by transnasal biopsy (figure 2). A combined treatment of chemotherapy and radiotherapy was suggested. Before treatment could be initiated, the patient died of a major hemorrhage in the tumor. Acknowledgment: The authors thank M.J. Flens for providing the pathology slides and explanation. |
Databáze: | OpenAIRE |
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