Steroidal and phenolic compounds from Sidastrum paniculatum (L.) Fryxell and evaluation of cytotoxic and anti-inflammatory activities
| Autor: | Delby Fernandes de Medeiros, Sílvia Rafaelli Ramos, Teresinha Gonçalves-Silva, Maria de Fátima, Paulo Roberto Cavalcanti Carvalho, Vanderlei de Souza, Silene Carneiro, Davi Antas, José Marcílio Sobral Cavalcante, Maria de Fátima Agra |
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| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Química Nova, Volume: 33, Issue: 4, Pages: 846-849, Published: 2010 Química Nova v.33 n.4 2010 Química Nova Sociedade Brasileira de Química (SBQ) instacron:SBQ Química Nova, Vol 33, Iss 4, Pp 846-849 (2010) |
| Popis: | Sidastrum paniculatum (L.) Fryxell belongs to the family Malvaceae and is popularly known as "malva roxa" or "malvavisco". The phytochemical study of the hexane, CHCl3 and EtOAc phases from the crude ethanol extract of S. paniculatum led to the isolation of six compounds: a mixture of β-sitosterol and stigmasterol, 4-methoxy-3-hydroxybenzoic acid, 4-methoxy-3-hydroxybenzaldehyde, N-trans-feruloyltyramine and kaempferol-3-O-β-D-(6''-E-p -coumaroyl) glucoside. The structural identification of the compounds was made on the basis of spectroscopic methods such as IR, ¹H and 13C NMR with the aid of including two-dimensional techniques, besides comparison with literature data. The β-sitosterol and stigmasterol mixture showed a significant anti-inflammatory activity. |
| Databáze: | OpenAIRE |
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