Fate of mild aortic valve disease after mitral valve intervention
| Autor: | Sachin Talwar, Arkalgud Sampath Kumar, Rajnish Juneja, Shiv Kumar Choudhary |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine Aortic valve medicine.medical_specialty Adolescent Heart disease Aortic Valve Insufficiency Regurgitation (circulation) Severity of Illness Index Disease-Free Survival Catheterization Aortic valve replacement Risk Factors Internal medicine Mitral valve Severity of illness medicine Humans Mitral Valve Stenosis Child Proportional Hazards Models Heart Valve Prosthesis Implantation business.industry Age Factors Mitral Valve Insufficiency Aortic Valve Stenosis Middle Aged medicine.disease Surgery Stenosis Treatment Outcome medicine.anatomical_structure Disease Progression Cardiology cardiovascular system Female Cardiology and Cardiovascular Medicine Complication business Follow-Up Studies |
| Zdroj: | The Journal of Thoracic and Cardiovascular Surgery. (3):583-586 |
| ISSN: | 0022-5223 |
| DOI: | 10.1067/mtc.2001.115916 |
| Popis: | Objective: This study was performed to assess the long-term outcome of untreated mild aortic valve disease present at the time of initial mitral valve intervention. Methods: A total of 284 patients with rheumatic heart disease aged 7 to 62 years (mean, 23.5 ± 12.2 years) who underwent mitral valve intervention and had mild aortic valve disease initially were followed up for 2 to 18 years (mean, 10.8 ± 3.7 years). At initial intervention, 232 patients had pure mild aortic regurgitation, and 52 patients had mild aortic stenosis with or without aortic regurgitation. Results: Among patients with mild aortic regurgitation initially, 11 (5%) patients progressed to moderate (n = 6) or severe (n = 5) regurgitation over an interval of 9 to 17 years (mean, 12.1 ± 2.8 years), and 1 patient had moderate aortic stenosis and severe aortic regurgitation after 10 years. Freedom from development of moderate-severe aortic valve disease in patients who initially had mild aortic regurgitation was 100%, 97.0% ± 1.7%, and 87.4% ± 4.6% at 5, 10, and 15 years, respectively. Seventeen (35%) patients with initial mild aortic stenosis (with or without regurgitation) had moderate or severe stenosis (with or without moderate-severe regurgitation) after an interval of 4.9 ± 3.8 years. Freedom from development of moderate-severe aortic valve disease in patients who initially had mild aortic stenosis was 75.6% ± 6.2%, 61.5% ± 8.5%, and 46.1% ± 11.2% at 5, 10, and 15 years, respectively. Ten patients required aortic valve replacement for aortic valve dysfunction. Conclusions: Mild aortic regurgitation present at the time of mitral valve intervention progresses very slowly and less frequently requires reintervention. However, mild aortic stenosis diagnosed initially progresses more often and more rapidly and thus needs closer follow-up. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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