End-Tidal CO2 in Patients with Panic Disorder, Stress-Related or Functional Syndromes, Versus Healthy Controls

Autor: Indra Ramakers, Maaike Van Den Houte, Lukas Van Oudenhove, Omer Van den Bergh, Katleen Bogaerts
Rok vydání: 2022
Předmět:
Zdroj: Applied Psychophysiology and Biofeedback. 48:149-157
ISSN: 1573-3270
1090-0586
DOI: 10.1007/s10484-022-09573-z
Popis: A dysregulated autonomic stress physiology is hypothesized to play an important role in the etiology and perpetuation of somatic symptoms that cannot be (fully) explained by an organic disease. The aim of this study was to focus on the role of the respiratory system. We examined end-tidal CO2 concentration (PetCO2) in healthy controls (n = 30), patients with panic disorder (n = 36), and patients with stress-related (overstrain; n = 35, burnout; n = 44) or functional syndromes [fibromyalgia (FM) and/or chronic fatigue syndrome (CFS); n = 36]. Participants went through a rest period and a respiratory challenge with recovery, whilst PetCO2 was continuously monitored by a capnograph. Taken together, our results suggest: (1) an overactive respiratory system to be a possible transdiagnostic underlying factor of overstrain, burnout, and panic disorder, and (2) the presence of a less active respiratory fight-flight response in the more chronic and severe functional syndromes (FM/CFS). ispartof: Applied Psychophysiology And Biofeedback vol:48 issue:2 ispartof: location:Germany status: Published online
Databáze: OpenAIRE
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