Freeze‐Dried microarterial replacement allografts in rabbits
| Autor: | Michael F. Pratt, William D. Horton, Harvey L. Bank, Marcia K. Schmehl |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Pilot Projects Femoral artery medicine.artery medicine Animals Transplantation Homologous Head and neck Electron microscopic Vascular Patency Lagomorpha biology business.industry Graft Survival Graft Occlusion Vascular Microsurgery biology.organism_classification Blood Vessel Prosthesis Surgery Femoral Artery Microscopy Electron Freeze Drying surgical procedures operative medicine.anatomical_structure Otorhinolaryngology Microscopy Electron Scanning Rabbit model Head and neck surgery Rabbits Tissue Preservation business Artery |
| Zdroj: | The Laryngoscope. 99:1020-1026 |
| ISSN: | 1531-4995 0023-852X |
| DOI: | 10.1288/00005537-198210000-00009 |
| Popis: | Microvascular techniques offer important alternatives for reconstructive head and neck surgery. To test the viability of freeze-dried allografts, a pilot experimental study was performed using the rabbit model. Freeze-dried preserved arterial allografts were implanted into femoral artery defects in eight subjects. After 6 weeks, all grafts were harvested and prepared for histological and electron microscopic analysis. Immediate patency was 100%. One subject was excluded on the third postoperative day. Of the seven remaining grafts, three (43%) were patent at 6 weeks. These results are comparable to previous data obtained using freeze-dried arterial allografts in the same animal model. Although further investigation is required, this pilot study suggests possible future application of cryopreserved vascular micrografts. |
| Databáze: | OpenAIRE |
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